On March 26, 1451, George Kastrioti Skanderbeg concluded an alliance with the king of Naples, Alfonso V of Aragon (1396-1458).

Through this act, the Spanish-Albanian relations, which were non-existent until then, began. Beginning his reign in 1442, following in the footsteps of his Norman predecessors, Alfonso V began implementing an ambitious policy towards the peninsula now called the Balkans.

Until the passing over of Skanderbeg in 1468, Alfonso V and then his son, Ferdinand II (1458-1494) continued to contribute to the war against the Ottomans. In return, Skanderbeg, along with 4,000 men, headed for Naples to help Ferdinand II against a D’Anjou rebellion of the nobility against him that almost broke out in the kingdom in 1462.

This military relationship was the basis of the diplomatic contacts that the Spaniards and Albanians maintained during the 16th century.

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